Instgra Tablet contains Dolutegravir 50 mg, a antiretroviral medicine used in the treatment of HIV infection. It works by blocking an enzyme called integrase, which HIV needs to multiply in the body. By preventing viral replication, Instgra helps maintain the immune system and reduces the risk of opportunistic infections.
This medicine is part of combination therapy. It is not a cure for HIV, but it helps manage the infection and improve long-term health, providing better quality of life in patients with compromised immune system.
How Instgra Tablet works?
Dolutegravir binds to the HIV integrase enzyme, stopping the virus from inserting its genetic material into human immune cells. This stops new virus from being produced. When taken consistently as prescribed, it can reduce viral load to undetectable levels, which lowers the risk of disease progression and transmission.
How to take Instgra Tablet
- Take the tablet once daily, with or without food.
- Swallow the tablet whole with water. Do not crush or chew.
- Take at the same time every day to maintain steady blood levels.
- Do not skip doses, as missing doses can lead to drug resistance.
Missed dose: Take it as soon as you remember on the same day. If it is almost time for the next dose, skip the missed one. Do not double the dose.
Suggestion and precations
Pregnancy and breastfeeding: . Dolutegravir has been used safely in many pregnancies, but your doctor may weigh benefits versus risk.
Kidney or liver disease: Inform your doctor if you have impaired kidney or liver function.
Other medications: Tell your doctor about all medicines, herbal supplements, or vitamins you are taking. Certain drugs may interfere with Dolutegravir.
Side effects
- Headache
- Dizziness
- Nausea
- Insomnia or sleep disturbances
- Fatigue
- Serious but rare side effects:
Regular monitoring of viral load is required, kidney, and liver function is recommended during treatment.
Storage
- Store tablets in a cool, dry place below 30°C.
- Keep out of reach of children.
- Protect from moisture and direct sunlight.
FAQ
Q. Can I stop Instgra when I feel better?
No. Stopping increases risk of viral resistance and disease progression. Always follow doctor’s advice.
Q. Can I take it with other HIV medicines?
Yes. It is designed to be part of combination antiretroviral therapy (ART). Your doctor will prescribe the appropriate regimen.
Q. How soon will it reduce viral load?
Some patients see reduction in weeks, but full effect is achieved with continuous therapy.
