Endace 160 Tablet is an oral medication containing Megestrol, a hormone-based medicine used to increase appetite and body weight in patients with chronic illness or cancer-related weight loss. It helps the body regain strength and improve quality of life when appetite is severely reduced.
Doctors prescribe it to patients with cancer, HIV, or other chronic conditions that cause cachexia having severe weight loss occuring due to loss of appetite, common in patients with such chronic disease.
How Endace 160 works
- Megestrol is a synthetic progestin. It works by affecting hormones that control appetite and metabolism.
- It signals the brain to increase hunger.
- It may help reduce inflammation that contributes to weight loss.
- In return, there is a visible increase in appetite and gradual weight gain over weeks of therapy.
How to take Endace 160 Tablet
- Take the tablet exactly as prescribed by your doctor.
- Swallow it whole with water. Do not crush or chew.
- Usually taken once daily, but your doctor may adjust the dose based on your condition.
- Take at the same time each day to maintain steady effect.
Missed dose: Take it as soon as you remember. Do not double the dose for a missed tablet.
Precautions and suggestion
- Inform your doctor if you have diabetes, liver problems, heart disease, or blood clot history.
- Pregnant women should avoid Endace, as Megestrol can harm the baby.
- Do not self-adjust the dose without your doctor’s guidance.
- Monitor for blood pressure changes, blood sugar, and swelling during treatment.
Side effects
- Nausea or vomiting
- Headache
- Fluid retention or swelling
- Edema
Storage
- Store in a cool, dry place below 30°C.
- Protect from direct sunlight and moisture.
- Keep out of reach of children.
FAQ
Q1. Can I take Endace for general weight gain?
No. It is only for patients with chronic condition and require certain weight for healthy treatment and improve quality of life.
Q2. How soon will I notice improved appetite?
Some patients notice appetite increase within a week. Weight gain may take a few weeks.

