What is Gonal F 450 IU Injection?
Gonal F 450 IU Injection is a fertility medicine made by Merck. It comes as a ready-to-use pen. The active ingredient is follitropin alfa, a lab-made form of FSH (follicle stimulating hormone). This is the same hormone your body uses to grow eggs each month.
The pen has 450 IU of the medication, that can be used in multiple doses. Doctors use it in IVF and other fertility treatments.
What does it treat?
The gonal f 450 iu pen is used when the ovaries need help making eggs. It is mainly for women going through IVF or fertility care.
Commonly used for:
- Women who do not release eggs on their own
- Women preparing for IVF, where many eggs are needed
- Some men with low sperm count, as part of hormone treatment
 How does Gonal F work?
Your ovaries need FSH to grow eggs. When your body makes too little, eggs do not develop.
Follitropin alfa copies this natural hormone. Once given, it tells the ovaries to start growing follicles. Each follicle holds an egg.
Over a few days, the eggs mature. In IVF, doctors can then collect these eggs for the next step.
Side effects
Most side effects are mild and pass on their own. Some people feel more than others.
- Headache
- Pain or redness at the injection spot
- Feeling bloated or full in the belly
- Mood changes
- Tender breasts
- Nausea
A serious problem to watch for is OHSS (ovarian hyperstimulation syndrome). This is when the ovaries swell too much. If you get sharp belly pain, fast weight gain, or trouble breathing, get help right away.
Who should not use the gonal f 450 iu pen?
This medicine is not safe for everyone. Do not use it if:
- You are already pregnant
- You have ovarian cysts not caused by PCOS
- You have unexplained bleeding from the vagina
- You have a tumour of the ovary, breast, womb, or brain
- You are allergic to follitropin alfa
Tell your doctor about any ovary, thyroid, or adrenal gland problems before you start.
How to store Gonal F 450 IU Injection
Keep the pen in the fridge at 2 to 8 degrees. Do not freeze it. Freezing ruins the hormone.
Once you start using the pen, you can keep it at room temperature for a short time if needed. Keep it in the box, away from light. Store it out of reach of children.
Price and delivery
- The gonal f 450 iu cost depends on your treatment plan, since dosing varies from person to person.
- Because this is a hormone injection, it ships in cold chain packing to keep the pen cold the whole way.
- Many patients worry the pen is hard to use. It is not. The dose dial is clear, and most people get the hang of it after the first try.
- Your doctor teach you how to use it.
