What is Infimab 100 mg injection?
Infimab 100 mg injection contains infliximab, a monoclonal antibody that targets TNF-alpha, a substance responsible for causing inflammation in the body. High TNF levels can lead to joint swelling, intestinal inflammation, and skin plaque formation. By blocking TNF-alpha, this medicine helps reduce inflammation gradually, which may improve symptoms and support healing over time.
Uses
Infimab 100mg injection is prescribed in several immune-related disorders.
- Rheumatoid Arthritis
- Ankylosing Spondylitis
- Psoriatic Arthritis
- Plaque Psoriasis
- Crohn’s Disease
- Ulcerative Colitis
- Mucosal ulcers
How does it work?
Infliximab is a chimeric monoclonal antibody. One end grabs TNF‑alpha in blood and tissue. TNF is the enzyme that causes damage, including joint inflammation, intestinal lining inflammation, and damage. When TNF is neutralised, the cascade that causes swelling, redness, diarrhea, and joint damage cools down. Over weeks lining of the intestine heals. Including joint damage progression slows over time.
Dose & Schedule pattern
| Condition | Starting Dose | Schedule After Start | Notes |
| Rheumatoid Arthritis | 3 mg/kg IV | Weeks 0, 2, 6, then every 8 weeks | Some need 5 mg/kg |
| Ankylosing Spondylitis, Psoriasis | 5 mg/kg IV | 0, 2, 6 weeks, then every 6–8 weeks | The interval can be tightened if flare. |
| Crohn’s disease | 5 mg/kg IV | 0, 2, 6 weeks, then every 8 weeks | Severe cases may escalate to 10 mg/kg |
| Pediatric Crohn’s (≥6 yrs) | 5 mg/kg IV | 0, 2, 6 weeks | Weight based |
Side effects
| Side effect | What you may feel | Simple help |
| Infusion reaction (during/within 1–2 h) | flushing, headache, itch, chest tight, mild BP drop | Slows or stops the drip, gives meds |
| Respiratory tract infections | cough, sore throat | Rest and hydrate |
| Headache/fatigue | dull ache, tired | Rest, hydrate |
| Abdominal pain (IBD) | mild cramp early | Usually settles as disease control improves |
| Nausea | uneasy stomach | light meals |
Precautions
- Arrive well hydrated
- Take light meal before infusion.
- Wear loose-sleeved clothes.
- Carry a list of all medicines.
- Avoid close contact with persons having active chickenpox, measles.
- Maintain good dental and oral hygiene
How to store?
- This product requires refrigeration.
- Store it in 2-8 Celsius.
- Unless required for usage, keep it refrigerator.
- Use once opened.
- Discard leftover medicine.
- Do not freeze.
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