What is Zynesp 40 mcg Injection?
Zynesp 40 mcg Injection contains darbepoetin, a protein that tells the body to make more red blood cells. It comes as a 40 mcg injection, given under the skin or into a vein. Zydus manufactures this medicine. Doctors call this group of medicines ESAs, short for erythropoiesis-stimulating agents. These medicines signal the bone marrow to make red blood cells.
What is Zynesp 40 mcg Injection used for?
This medicine treats anemia. Anemia is a condition where the blood does not carry enough oxygen because red blood cell counts are too low. Doctors reach for it in cases such as:
- Anemia linked to long-term kidney disease, including people on dialysis
- Anemia caused by chemotherapy in some cancer patients
People with anemia often feel weak, breathless, or pale. Zynesp 40 helps bring red blood cell counts back toward a normal range. This helps the body get the oxygen it needs.
Why Zynesp 40 mcg Injection works
Kidneys normally release a hormone called erythropoietin. This hormone tells the bone marrow to produce red blood cells. When kidneys are damaged, they make less of this hormone. Red blood cell counts then fall. Darbepoetin copies this hormone closely enough that the bone marrow responds the same way. Over a few weeks, blood counts begin climbing back up.
People switching from older anemia injections often ask why this one is used less often. Darbepoetin stays active in the body longer than older versions. It works over a longer stretch of time.
Side effects
Most people manage fine on this injection. Some side effects can come up:
- headache
- joint pain or muscle aches
- swelling or redness at the injection spot
- rise in blood pressure
- feeling tired despite treatment
In rare cases, darbepoetin can raise the risk of blood clots or cause a serious allergic reaction. If you notice chest pain, sudden swelling, or trouble breathing, get medical help right away.
Who should not use Zynesp 40 mcg Injection
- People whose blood pressure is not under control
- Anyone allergic to darbepoetin or similar proteins
- Pregnant or breastfeeding women, unless a doctor confirms it is safe
- People with certain cancers, since raising red blood cell counts is not right for every cancer type. Share your full cancer history with your doctor before starting.
How to store this injection?
- Keep the vial in a fridge between 2°C and 8°C.
- Do not freeze it.
- Keep it away from direct light.
- Do not shake it.
- If mixing is needed, swirl it gently as shaking vigoursly damage the chain of protein.
- Once taken out of the fridge, use it immediately. Avoid keeping outside incase injection is not ready for use.
Price and Availability?
Zynesp 40 mcg Injection is priced at Rs.1150 per injection. You can place your order through IVFInjection, with delivery available in Delhi, Noida, Gurugram, Ghaziabad, and Faridabad. This is a temperature-sensitive injection, so it ships in insulated packaging to stay at the right temperature until it reaches you.

